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Neroev, V. V.; Iomdina, E. N.; Khandzhyan, A. T.; Khodzhabekyan, N. V.; Sengaeva, M. D.; Ivanova, A. V.; Seliverstov, S. V.; Teplyakova, K. O.; Goltsman, G. N. |
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Experimental study of the effect of corneal hydration and its biomechanical properties on the results of photorefractive keratectomy |
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Journal Article |
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Year |
2021 |
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Vestn. Oftalmol. |
Abbreviated Journal |
Vestn. Oftalmol. |
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137 |
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3 |
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68-75 |
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THz scanning, cornea, photorefractive keratectomy, medicine |
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Water content in the cornea may affect the outcome of its excimer laser ablation, especially in presbyopic patients with myopic refraction. This hypothesis can be tested by scanning the cornea in the terahertz (THz) range to determine its hydration level.
Purpose: To study the effect of hydration of the cornea determined by non-contact THz scanning and its biomechanical parameters on the results of photorefractive keratectomy (PRK) in an experiment.
Material and methods: PRK was performed using the Nidek EC-5000 QUEST excimer laser on 8 rabbit eyes. Corneal hydration was evaluated by determining the reflection coefficient (RC) in the THz electromagnetic radiation range before PRK, after 3-5 days, and after 1, 2, 3, and 4 months. Clinical examination included autorefractometry, assessment of corneal thickness and other anatomical and optical parameters of the anterior eye segment (Galilei G6, Ziemer Ophthalmic Systems AG 6.0.2, Switzerland), measurement of corneal hysteresis (CH) and corneal resistance factor (CRF) using the Ocular Response Analyzer (ORA; Reichert, USA), as well as tear production (Schirmer test).
Results: The initial water content in the cornea has a significant effect on the thickness of the removed layer, i.e. on the PRK effect, with correlation coefficient of Rs= -0.976 (p<0.01). The correlation between CH and the ablation depth is less pronounced (Rs=0.643), and CRF had no correlation with it (Rs= -0.089). Biomechanical indicators of the cornea depend on its hydration: changes in CH and CRF after excimer laser ablation qualitatively coincide with changes in RC, the correlation coefficient between RC and the initial value of CH is R= -0.619 (moderate negative correlation).
Conclusion: THz scanning is an effective non-contact technology for monitoring corneal hydration level. The mismatch of the hypoeffect of keratorefractive excimer laser intervention planned for patients with presbyopia with the actual outcome can be caused by individual decrease in the initial water content in the cornea. |
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Ожегов, Р.В.; Горшков, К.Н.; Окунев, О.В.; Гольцман, Г.Н. |
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Сверхпроводниковый смеситель на эффекте электронного разогрева как элемент матрицы системы построения тепловых изображений |
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2010 |
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Письма в Журнал технической физики |
Abbreviated Journal |
Письма в ЖТФ |
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36 |
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21 |
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70-78 |
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Исследована возможность использования матрицы чувствительных элементов на гиперполусферической линзе диаметром 12 mm в тепловизоре терагерцевого диапазона частот. Получены размеры области на линзе, приемлемой для расположения матрицы, в которой шумовая температура приемника меняется в пределах 16% от средней. Диаметр этой области составил 3.3% диаметра линзы.Получены отклонения основного лепестка диаграммы направленности, которые составили ±1.25â—<a6> от направления с оптимальным положением смесителя. Флуктуационная чувствительность приемника в эксперименте составила 0.5 K на частоте 300 GHz. |
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Korneev, A.; Korneeva, Y.; Florya, I.; Voronov, B.; Goltsman, G. |
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NbN nanowire superconducting single-photon detector for mid-infrared |
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2012 |
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Phys. Procedia |
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Phys. Procedia |
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36 |
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72-76 |
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NbN SSPD, SNSPD |
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Superconducting single-photon detectors (SSPD) is typically 100 nm-wide supercondiucting strip in a shape of meander made of 4-nm-thick film. To reduce response time and increase voltage response a parallel connection of the strips was proposed. Recently we demonstrated that reduction of the strip width improves the quantum effciency of such a detector at wavelengths longer than 1.5 μm. Being encourage by this progress in quantum effciency we improved the fabrication process and made parallel-wire SSPD with 40-nm-wide strips covering total area of 10 μm x 10 μm. In this paper we present the results of the characterization of such a parallel-wire SSPD at 10.6 μm wavelength and demonstrate linear dependence of the count rate on the light power as it should be in case of single-photon response. |
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1875-3892 |
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1382 |
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Третьяков, И.В.; Рябчун, С.А.; Каурова, Н.С.; Ларионов, П.А.; Лобастова, А.А.; Воронов, Б.М.; Финкель, М.И.; Гольцман, Г.Н. |
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Оптимальная поглощенная мощность гетеродина для терагерцового сверхпроводникового NbN смесителя на электронном разогреве |
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2010 |
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Письма в Журнал технической физики |
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Письма в ЖТФ |
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36 |
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23 |
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78-84 |
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Представлены результаты измерений поглощенной мощности гетеродина малошумящим широкополосным смесителем на эффекте электронного разогрева в резистивном состоянии сверхпроводниковой ультратонкой пленки NbN. Оптимальная поглощенная мощность гетеродина составила около 100 nW на частоте 2.5 THz. |
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703 |
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Расулова, Г.К.; Брунков, П.Н.; Пентин, И.В.; Ковалюк, В.В.; Горшков, К.Н.; Казаков, А.Ю.; Иванов, С.Ю.; Егоров, А.Ю.; Саксеев, Д.А.; Конников, С.Г. |
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Взаимная синхронизация двух связанных генераторов автоколебаний на основе сверхрешеток GaAs/AlGaAs |
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2011 |
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Журнал технической физики |
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ЖТФ |
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81 |
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80-86 |
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Проведено исследование взаимодействия генераторов автоколебаний на основе 30-периодной слабосвязанной сверхрешетки GaAs/AlGaAs. Воздействие одного генератора автоколебаний на другой осуществлялось при заданном постоянном смещении в отсутствие в одном из них генерации автономных колебаний. Показано, что вынужденные колебания в захватывающем генераторе возникают из-за возбуждения колебаний в системе связанных осцилляторов, образующих границу электрополевого домена на частоте одной из высших гармоник вынуждающего колебания. |
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