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Morozov, P.; Lukina, M.; Shirmanova, M.; Divochiy, A.; Dudenkova, V.; Gol'tsman, G. N.; Becker, W.; Shcheslavskiy, V. I. |
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Title |
Singlet oxygen phosphorescence imaging by superconducting single-photon detector and time-correlated single-photon counting |
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Journal Article |
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Year |
2021 |
Publication |
Opt. Lett. |
Abbreviated Journal |
Opt. Lett. |
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46 |
Issue |
6 |
Pages |
1217-1220 |
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Keywords |
SSPD, SNSPD, applications |
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Abstract |
This Letter presents, to the best of our knowledge, a novel optical configuration for direct time-resolved measurements of luminescence from singlet oxygen, both in solutions and from cultured cells on photodynamic therapy. The system is based on the superconducting single-photon detector, coupled to the confocal scanner that is modified for the near-infrared measurements. The recording of a phosphorescence signal from singlet oxygen at 1270 nm has been done using time-correlated single-photon counting. The performance of the system is verified by measuring phosphorescence from singlet oxygen generated by the photosensitizers commonly used in photodynamic therapy: methylene blue and chlorin e6. The described system can be easily upgraded to the configuration when both phosphorescence from singlet oxygen and fluorescence from the cells can be detected in the imaging mode. Thus, co-localization of the signal from singlet oxygen with the areas inside the cells can be done. |
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0146-9592 |
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PMID:33720151 |
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1221 |
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Nebosis, R. S.; Heusinger, M. A.; Semenov, A. D.; Lang, P. T.; Schatz, W.; Steinke, R.; Renk, K. F.; Gol'tsman, G. N.; Karasik, B. S.; Gershenzon, E. M. |
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Title |
Ultrafast photoresponse of an YBa2Cu3O7-δ film to far-infrared radiation pulses |
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Journal Article |
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Year |
1993 |
Publication |
Opt. Lett. |
Abbreviated Journal |
Opt. Lett. |
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18 |
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2 |
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96-97 |
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Keywords |
YBCO HTS detectors |
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We report the observation of an ultrafast photoresponse of a high-T(c), film to far-infrared radiation pulses. The response of a sample, consisting of a current-carrying structured YBa(2)Cu(3)O(7-delta) film cooled to liquid-nitrogen temperature, was studied by use of ultrashort laser pulses from an optically pumped far-infrared laser in the frequency range from 0.7 to 7 THz. We found that the response time was limited by the time resolution, 120 ps, of our electronic registration equipment. |
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0146-9592 |
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PMID:19802049 |
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1660 |
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Finkel, M. I.; Maslennikov, S. N.; Gol'tsman, G. N. |
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The concept of the receiving complex for the “Millimetron” space radio telescope |
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Journal Article |
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2007 |
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Radiophys. Quant. Electron. |
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Radiophys. Quant. Electron. |
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50 |
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10-11 |
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837-846 |
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HEB, applications, Millimetron, VLBI |
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We consider the current status of research in the development of a submillimeter and far-infrared receiving instrument and propose promising solutions for the receivers of the spaceborne telescope “Millimetron,” which allow one to realize comprehensively the opportunities given by this international project administrated by the Astrospace Center of the P. N. Lebedev Physical Institute of the Russian Academy of Sciences. |
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0033-8443 |
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411 |
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Smirnov, A. V.; Larionov, P. A.; Finkel, M. I.; Maslennikov, S. N.; Voronov, B. M.; Gol'tsman, G. N. |
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Title |
NbZr films for THz phonon-cooled HEB mixers |
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Conference Article |
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2008 |
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Proc. 19th Int. Symp. Space Terahertz Technol. |
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Proc. 19th Int. Symp. Space Terahertz Technol. |
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44-47 |
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HEB, NbZr, material search |
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Groningen, Netherlands |
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577 |
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Finkel, M. I.; Maslennikov, S. N.; Vachtomin, Yu. B.; Svechnikov, S. I.; Smirnov, K. V.; Seleznev, V. A.; Korotetskaya, Yu. P.; Kaurova, N. S.; Voronov, B. M.; Gol'tsman, G. N. |
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Hot electron bolometer mixer for 20 – 40 THz frequency range |
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Conference Article |
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2005 |
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Proc. 16th Int. Symp. Space Terahertz Technol. |
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Proc. 16th Int. Symp. Space Terahertz Technol. |
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393-397 |
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IR NbN HEB mixers |
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The developed HEB mixer was based on a 5 nm thick NbN film deposited on a GaAs substrate. The active area of the film was patterned as a 30×20 μm 2 strip and coupled with a 50 Ohm coplanar line deposited in situ. An extended hemispherical germanium lens was used to focus the LO radiation on the mixer. The responsivity of the mixer was measured in a direct detection mode in the 25÷64 THz frequency range. The noise performance of the mixer and the directivity of the receiver were investigated in a heterodyne mode. A 10.6 μm wavelength CW CO 2 laser was utilized as a local oscillator. |
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Göteborg, Sweden |
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369 |
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