TY  - JOUR
AU  - Anosov, A. A.
AU  - Nemchenko, O. Yu
AU  - Less, Yu A.
AU  - Kazanskii, A. S.
AU  - Mansfel'd, A. D.
PY  - 2015
DA  - 2015//
TI  - Possibilities of acoustic thermometry for controlling targeted drug delivery
JO  - Acoust. Phys.
SP  - 488
EP  - 493
VL  - 61
IS  - 4
KW  - acoustic thermometry
KW  - liposome suspension
KW  - thermography
AB  - Model acoustic thermometry experiments were conducted during heating of an aqueous liposome suspension. Heating was done to achieve the liposome phase transition temperature. At the moment of the phase transition, the thermal acoustic signal achieved a maximum and decreased, despite continued heating. During subsequent cooling of the suspension, when lipids again passed through the phase transition point, the thermal acoustic signal again increased, despite a reduction in temperature. This effect is related to an increase in ultrasound absorption by the liposome suspension at the moment of the lipid phase transition. The result shows that acoustic thermography can be used to control targeted delivery of drugs mixed in thermally sensitive liposomes, the integrity of which is violated during heating to the phase transition temperature.
UR  - https://doi.org/10.1134/S1063771015040028
DO  - 10.1134/S1063771015040028
N1  - exported from refbase (https://db.rplab.ru/refbase/show.php?record=1130), last updated on Fri, 28 Jul 2017 13:45:09 -0500
ID  - Anosov_etal2015
ER  -